RE6 contains not 1, but 4 long campaigns telling the story of those who fight BOWs. You can choose whomever you want: Leon, Helena, Chris, Sherry or Wesker's son. All the stories are interwoven and you can see the action from each character's perspective. You ave lots of moments of intense action, you have great cinematics and you have to use your melee abilities to escape from some dangerous situations.
Having killed bosses you gain skill points which can be used to unlock different improvements.
I enjoyed all the campaigns and the way they are linked together.